Sudan is the largest country in Africa. It has been ravaged by two decades of conflict between the Arab Muslim government in the North and the majority black Christian and Animist South fighting for independence. An entire region, Darfur, has been destroyed by a war that has degenerated into one of the worst conflicts in Africa.

Life expectancy in Sudan is 57 years. The mortality rate for children under the age of five is approximately 10.7%. Fifty percent of the population has no access to lifesaving medications. The doctor-to-patient ratio is 16:100,000.

In 2004 EMERGENCY intervened in Sudan to support the hospitals in Mellit and Al Fashir, in Northern Darfur, by renovating and equipping the emergency surgical block and ward.

In 2005 EMERGENCY opened a Paediatric Centre in Mayo Internally Displaced People (IDP) camp, a few kilometres from the capital Khartoum. The Centre provides free of charge primary healthcare to children up to 14 years of age.

In the same year, again nearby the capital, EMERGENCY started to build a Centre for Cardiac Surgery in order to provide highly specialized free medical and surgical assistance to patients from Sudan and its neighbouring countries.

The Salam Centre for Cardiac Surgery started its activities in 2007. It is linked to a network of Paediatric Centres where EMERGENCY's international cardiologists carry out the screening and follow-up of children and adult heart patients that are transferred to Khartoum for surgery.

In July 2010 EMERGENCY opened a Paediatric Centre in Nyala. The Centre's activities are currrently suspended 2011, following the kidnapping of a staff member who was released in December 2011 after 4 months of imprisonment. 

In December 2011, the Paediatric Centre in Port Sudan started activities.

Since the beginning of its activities in Sudan, EMERGENCY has treated over 325,697 patients.